Van de Ven Double Halts Everton's Run at Brand New Stadium
Micky van de Ven emerged as the first backline player to score twice in a Premier League match for Tottenham since Jan Vertonghen in spring 2013.
Match summary
The Spurs defender heads home twice in opening period
The home side's defender has goal ruled after VAR review
Pape Matar Sarr scores final goal in dying moments
The defeat is Everton's first at Hill Dickinson Stadium
Micky van de Ven found the net on two occasions as Tottenham prolonged their unbeaten run in away games in the top division and delivered Everton their first defeat at Hill Dickinson Stadium.
Everton were unbeaten in their five previous fixtures at their new ground at the dockside location, having departed their historic home behind after more than a century at the conclusion of the previous campaign.
But Tottenham's leader Van de Ven struck on two occasions from corners in the first half to place their strong form at risk, and they were failed to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - headed home a third to put the game to bed.
Jake O'Brien believed he had levelled the tally a short while after the defender's first goal, glancing a bullet header past Guglielmo Vicario from an set-piece.
The Portuguese striker, in the meantime, failed to convert a number of chances, while the Italian goalkeeper made a series of excellent saves to ensure Tottenham went five matches on the road without defeat in the Premier League.
But the video assistant referee intervened, advising Craig Pawson to check the goal on the screen and the official decided that Jack Grealish and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
This victory moves the manager's side up to third in the division, five points off north London rivals and table-toppers Arsenal.
The Merseyside club stay 14th and sit six points ahead of the relegation zone.
Spurs breakdown: The defender excels in role at each end of pitch
Following a drab midweek display in the Champions League against Monaco, where they mustered a only attempts on goal, the manager opted for Randal Kolo Muani up front instead of ex-Everton forward the Brazilian.
The new arrival was failed to make much of an impact before being substituted for the substitute after 60 minutes on the field, but it emerged he wasn't needed in the end.
Defender the Dutchman transformed into an offensive threat to be reckoned with.
Tottenham's first goal came from a well-worked set-piece play, with Rodrigo Bentancur heading the ball back across the six-yard box for an free the defender to score.
And Ven de Ven - stepping up as captain in Cristian Romero's absence - notched his second in first-half stoppage time as he outjumped Jordan Pickford to head home.
Van de Ven was equally impressive in defensive duties, combining well with Kevin Danso as the duo dealt excellently with the 34 crosses sent their way by the opposition.
Toffees breakdown: Toffees missing striker's instinct
The club's recent stadium had been a fortress, but it seems the freshness may have worn off somewhat and supporters flocked to the gates after the midfielder's third for Tottenham.
The break in the team's winning streak at home won't be a massive worry for the manager, but their striker situation will be.
Beto and Thierno Barry - the Toffees' pair of recognised centre-forwards - had netted just one league goal combined before the weekend's match.
And they were unable to contribute to that miserable record on a wet and gloomy night on Merseyside.
The striker's performance was summed up when he opted to bicycle-kick a golden opportunity from close range, despite having room and time to reposition for a simpler attempt that would have tested Vicario.
Barry, as well, failed to make an impact after replacing Beto in the second half.
It was not for a shortage of chance. Most of the home side's attacks came through Grealish and the forward, who tirelessly delivered threatening balls into the Tottenham box.
Upcoming fixtures for these two sides?
Everton: Moyes' men travel to Sunderland in the top flight on early November at 20:00 GMT.
Tottenham: The London club travel to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup match against the Magpies.